{"count":565,"next":null,"previous":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/grants_received/?limit=100&offset=440","results":[{"grant_id":"360G-Wellcome-320187_Z_24_Z","data":{"id":"360G-Wellcome-320187_Z_24_Z","title":"“Breaking the inverse laws”: Accelerating the health equity impact of prevention and control interventions for infectious diseases in Africa  ","Region":"London","currency":"GBP","awardDate":"2025-05-19T00:00:00+00:00","Internal ID":"320187/Z/24/Z","description":"Despite their potential to accelerate infectious disease prevention and control, health innovations often exacerbate rather than reduce health inequity, both between countries and within them. As researchers and practitioners working in the region most affected by infectious disease, sub- Saharan Africa, we are frustrated when richer countries and more advantaged groups are better enabled to take advantage of new technologies, compounding patterns of infectious disease risk and poorer access to health services among disadvantaged populations. We refer to the combined forces underpinning these repeated experiences as \"the inverse laws\". Determinants include structural factors, markets, health policies, programme implementation, behavioural and social factors and epidemiological dynamics. These determinants interact in complex ways, unique to infections, limiting the utility of existing health equity frameworks. But, the inverse laws are not inevitable. Counter-cases are found. The determinants are modifiable. We will use interdisciplinary, theory- informed analysis to interpret historical patterns and possible future trends, developing a new infectious disease health equity framework. We will conduct mixed-method, country-level case studies to investigate how to “break the inverse laws” for four major infectious diseases: HIV, HPV, measles and outbreak-prone infections. Findings will be actionable, disseminated through a cross-sectoral community of practice to ensure new advances benefit all.","plannedDates":[{"endDate":"2030-04-30T00:00:00+00:00","startDate":"2025-11-01T00:00:00+00:00"}],"amountAwarded":3599912,"Financial Year":"2024/25","Lead Applicant":"Prof James R Hargreaves","grantProgramme":[{"title":"Discovery Award"}],"Applicant Surname":"Hargreaves","Approval Committee":"DSV Interview Committee","Other Applicant(s)":"Dr Ruoran Li, Dr Mwelwa Muleba Phiri, Dr Ruoran Li, Ms Jessica M Ochalek, Dr Elizabeth Fearon, Prof Frank Courteney Tanser, Prof Shelley S Lees, Prof Ed Clarke, Ms Primrose Matambanadzo","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"Yes","Total amount including partnership funding":3599912},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-320877_Z_24_Z","data":{"id":"360G-Wellcome-320877_Z_24_Z","title":"Not enough and too many: professional personhood among Africa's paradoxically surplus health workers  ","Region":"London","currency":"GBP","awardDate":"2025-05-19T00:00:00+00:00","Internal ID":"320877/Z/24/Z","description":"By 2030, it is anticipated that Africa will face a shortage of nearly 6.1 million health workers. Simultaneously, approximately 700,000 health workers on the continent are expected to be without formal employment. Under current projections, this paradoxical surplus of health workers will comprise almost a quarter of Africa’s health workforce. \"Not Enough and Too Many\" is a bold mixed-methods study across West, East and Southern Africa. It asks: what are the global, national and local contingencies that have led to this paradoxical surplus; what are the consequences for individuals and services; and how can we enable the incorporation of this surplus into health systems? Drawing together scholars and methods from anthropology and public health, we will explore how unemployment, underemployment and precarious employment among health workers intersects with personhood and socio-economic relations; map the informal livelihood opportunities offered by pluralistic health systems; and examine the political economy underpinning policy on health worker employment in Uganda, Nigeria and Zambia. Our ultimate goals are to change narratives so that the paradoxical surplus of health workers takes its place as a critical issue in global health, and to support collaborations between academics, policy-makers, activists and health workers to reverse the trend.","plannedDates":[{"endDate":"2030-08-31T00:00:00+00:00","startDate":"2025-09-01T00:00:00+00:00"}],"amountAwarded":2559999,"Financial Year":"2024/25","Lead Applicant":"Dr Eleanor Hutchinson","grantProgramme":[{"title":"Discovery Award"}],"Applicant Surname":"Hutchinson","Approval Committee":"DSV Interview Committee","Other Applicant(s)":"Dr Sanny Mulubale, Prof Chidi Hyginus Ugwu, Dr Freddy Eric Kitutu","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":2559999},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-320878_Z_24_Z","data":{"id":"360G-Wellcome-320878_Z_24_Z","title":"CONNECT - Cohort and environmental data integration for epidemiological innovation  ","Region":"London","currency":"GBP","awardDate":"2025-05-19T00:00:00+00:00","Internal ID":"320878/Z/24/Z","description":"While the world faces an escalating climate crisis, our knowledge of the health risks of environmental stressors and climate change remains limited. CONNECT will bridge recent advances in geospatial modelling and health data infrastructure to revolutionise the research context in this field. The project, led by the EHM-Lab at LSHTM, is built on a well-structured research programme. First, novel GIS and machine-learning techniques will be applied to reconstruct hyper-resolution maps of environmental and climatic stressors across the UK. The team will then develop an innovative linkage scheme as well as cutting-edge statistical and computational techniques to integrate and analyse these data within the major large-scale UK cohort platforms. Various applications of the framework will be demonstrated in real-data case studies. Finally, methodologies, data, and training material will be released in open- access repositories and tutorials. This work will connect detailed individual- level measures of environmental exposures and physical environment with socio- economic indicators, medications and therapies, health events/conditions, and metabolic/genomic profiles in cohorts of millions of patients/participants. These resources will unlock unparalleled opportunities to address knowledge gaps, allowing investigations of complex mechanisms linking environment, climate, and health, and eventually informing public health and climate policies, reshaping this research field for decades to come.","plannedDates":[{"endDate":"2032-09-30T00:00:00+00:00","startDate":"2025-10-01T00:00:00+00:00"}],"amountAwarded":2501393,"Financial Year":"2024/25","Lead Applicant":"Prof Antonio Gasparrini","grantProgramme":[{"title":"Discovery Award"}],"Applicant Surname":"Gasparrini","Approval Committee":"DSV Interview Committee","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":2501393},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-321702_Z_24_Z","data":{"id":"360G-Wellcome-321702_Z_24_Z","title":"Quantifying childhood cancer burden in Tanzania: optimising use of multi- hospital electronic datasets and implications for cancer care and outcomes  ","Region":"London","currency":"GBP","awardDate":"2025-07-15T00:00:00+00:00","Sponsor(s)":"Prof Bernard Rachet","Internal ID":"321702/Z/24/Z","description":"Childhood cancer incidence in Africa is estimated to be similar to that of childhood malaria and twice as high as HIV, but without supportive care priority. By 2050, Africa will bear 50% of the global childhood cancer burden, making urgent action critical. Despite being curable in high-income countries, 5-year survival is only 8% in East-Africa, compared to 90% in the UK. Limited comprehensive data makes it difficult to assess the respective roles of detection, diagnosis, and treatment in poor outcomes. National childhood surveillance programme is required to achieve the World Health Organisation’s target of increasing childhood cancer 5-year survival to at least 60% by 2030. This project will generate the first quantification of Tanzania’s childhood cancer burden, its determinants, and drivers of poor outcomes by optimising a multi-hospital electronic health record system. I will achieve this by (1) using state-of-the-art epidemiological and statistical techniques to maximise data use; (2) and developing actionable recommendations for sustaining childhood cancer epidemiologic surveillance. Project outputs include an interactive dashboard reporting key indicators (e.g., incidence, mortality, and survival) to guide clinicians and public health interventions. The project will lay a foundation for ongoing surveillance, supporting efforts to reduce preventable cancer deaths in Tanzania and beyond.","plannedDates":[{"endDate":"2030-12-31T00:00:00+00:00","startDate":"2026-01-01T00:00:00+00:00"}],"amountAwarded":836555,"Financial Year":"2024/25","Lead Applicant":"Dr Wende Clarence Safari","grantProgramme":[{"title":"Early-Career Award"}],"Applicant Surname":"Safari","Approval Committee":"ECA Interview Panel","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":836555},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-324097_Z_25_Z","data":{"id":"360G-Wellcome-324097_Z_25_Z","title":"Open Access Award 2025  ","Region":"London","currency":"GBP","awardDate":"2024-12-31T00:00:00+00:00","Internal ID":"324097/Z/25/Z","description":"No description available","plannedDates":[{"endDate":"2025-12-31T00:00:00+00:00","startDate":"2025-01-01T00:00:00+00:00"}],"amountAwarded":165292,"Financial Year":"2024/25","Lead Applicant":"David Archer","grantProgramme":[{"title":"Open Access Award"}],"Applicant Surname":"Archer","Approval Committee":"Open Access Block Award recommendation meeting","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":165292},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-324265_Z_25_Z","data":{"id":"360G-Wellcome-324265_Z_25_Z","title":"Characterising colonisation and transmission of Multi-Drug Resistant Gram- negative organisms in maternal care in Uganda - GRam negative Resistance In Pregnancy (GRIP).  ","Region":"London","currency":"GBP","awardDate":"2025-06-12T00:00:00+00:00","Sponsor(s)":"Prof Jaime Vera, Prof Gail Davey","Internal ID":"324265/Z/25/Z","description":"Infection is a common cause of maternal and neonatal death in Africa, and both mother and child are at increased risk of healthcare-associated infections (HAI). Multi-drug resistant Gram-negative bacteria (MDR-GNB) have acquired non-susceptibility to at least one agent in three or more antimicrobial categories, severely limiting treatment options. Antimicrobial resistance (AMR) is a threat to the health of pregnant women and infants. Colonisation with MDR-GNB bacteria may precede infection. The hospital environment can serve as reservoir for MDR-GNB, with a clean healthcare environment preventing colonisation and infection. The frequency of pregnant and postpartum women’s colonization with MDR-GNB during healthcare encounters and the hospital environment’s role in transmission pathways is poorly understood. Understanding the extent of MDR-GNB contamination in hospital environments can set benchmarks for monitoring and evidence-based cleaning standards, averting outbreaks and HAI. I aim to characterise the prevalence of colonisation with MDR-GNB in a cohort of pregnant women and neonates in Uganda and investigate the role of the hospital environment in acquisition of MDR-GNB around the time of delivery. I will identify and develop context appropriate, effective cleaning tools and assess their impact on MDR-GNB burden, developing context- appropriate environmental hygiene standards applicable to healthcare facilities across Africa","plannedDates":[{"endDate":"2027-11-02T00:00:00+00:00","startDate":"2024-11-03T00:00:00+00:00"}],"amountAwarded":0,"Financial Year":"2024/25","Lead Applicant":"Dr Lauren Hookham","grantProgramme":[{"title":"PhD Studentship for Health Professionals"}],"Applicant Surname":"Hookham","Approval Committee":"Discretionary Award decision meeting","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":0},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-324545_Z_25_Z","data":{"id":"360G-Wellcome-324545_Z_25_Z","title":"The transmission dynamics of Streptococcus pyogenes within the classrooms, households and environment of primary school-aged children in The Gambia.  ","Region":"London","currency":"GBP","awardDate":"2025-06-12T00:00:00+00:00","Sponsor(s)":"Prof Michael Marks","Internal ID":"324545/Z/25/Z","description":"Group A Streptococcus (GAS) has a large global burden. The dynamics of acquisition for both infection and asymptomatic colonisation are unknown, yet essential to understand for designing and assessing future preventative interventions. I will conduct an 8-month cohort study of primary school-aged pupils from three classes in The Gambia, to describe the patterns and determinants of GAS transmission. Fortnightly throat and skin swabs will be cultured and GAS confirmed by MALDI-TOF. Cough plates will be taken from all clinical cases of pharyngitis and wound swabs from pyoderma. Reactive classroom and index-case household surveys will be conducted, with classroom environmental sampling. All samples will undergo quantitative polymerase chain reaction (qPCR), with downstream emm-typing and whole genome sequencing (WGS) of detected GAS. Primary objectives: 1) To establish an accurate prevalence and incidence of pharyngeal and skin infection and asymptomatic colonisation of GAS in primary school-aged children in The Gambia. 2) To calculate the secondary attack rate of GAS infection/colonisation, through temporal and molecular linkage, in classmates and household members of index cases of pharyngitis and pyoderma. 3) To investigate whether bacterial load in the pharynx or skin is a driver of onward transmission and/or environmental detection, comparing symptomatic cases with asymptomatic colonisation.","plannedDates":[{"endDate":"2028-05-05T00:00:00+00:00","startDate":"2024-11-06T00:00:00+00:00"}],"amountAwarded":0,"Financial Year":"2024/25","Lead Applicant":"Dr Edward Monk","grantProgramme":[{"title":"PhD Studentship for Health Professionals"}],"Applicant Surname":"Monk","Approval Committee":"Discretionary Award decision meeting","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":0},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-324905_Z_25_Z","data":{"id":"360G-Wellcome-324905_Z_25_Z","title":"Advancing social media data science to examine the causal relationship between social media content and adolescent health-risk behaviours  ","Region":"London","currency":"GBP","awardDate":"2025-07-15T00:00:00+00:00","Sponsor(s)":"Prof Mark Petticrew, Prof Amy Orben","Internal ID":"324905/Z/25/Z","description":"Social media platforms like TikTok may negatively shape adolescents' health behaviours, contributing to health inequalities. Exposure to alcohol, drug use, and anti-social behaviour (ADA) content on social media correlates with increased offline engagement in these behaviours. However, existing research relies on biased measures (e.g., time-use diaries, self-reports), which fail to capture the complexity of content exposure, limiting causal claims and evidence-based policy. Guided by a Policy Advisory Group - including stakeholders from Ofcom, the Department for Science, Innovation, and Technology - and Youth Advisory Groups, this project aims to address critical policy priorities by: (1) Developing innovative methodologies to accurately measure real-time social media content exposure by using a hybrid human- generative AI approach to identify ADA-content in TikTok data donations (obtained via the TikTok Application Programming Interface) combined with Ecological Momentary Assessment. (2) Assessing the causal effects of ADA- content on offline ADA-behaviours in adolescents (ages 13-24) from the socioeconomically and ethnically diverse Born in Bradford Age of Wonder and SmartHealth Young Adult Studies. Ultimately, the project will integrate public voices for real-world impact, inform public health strategies and legislation, and advance knowledge via a public engagement campaign featuring influential figures (i.e., United Nations, Idris Elba), high-impact publications, and policy briefings.","plannedDates":[{"endDate":"2031-02-26T00:00:00+00:00","startDate":"2026-02-27T00:00:00+00:00"}],"amountAwarded":753083,"Financial Year":"2024/25","Lead Applicant":"Dr Amrit Kaur Purba","grantProgramme":[{"title":"Early-Career Award"}],"Applicant Surname":"Purba","Approval Committee":"ECA Interview Panel","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"Yes","Research conducted at multiple locations?":"Yes","Total amount including partnership funding":753083},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-327785_Z_25_Z","data":{"id":"360G-Wellcome-327785_Z_25_Z","title":"ANH Academy Week bursary support  ","Region":"London","currency":"GBP","awardDate":"2025-04-01T00:00:00+00:00","Internal ID":"327785/Z/25/Z","description":"Since 2015, the Agriculture, Nutrition & Health (ANH) Academy has evolved into a global community of over 11,000 members from 160 countries, working towards sustainable and equitable food systems. Nearly 70% of members are based in Africa and Asia, with over 60% being women. The key objectives of the ANH Academy are to: \\- Build an interdisciplinary community to share innovative research. \\- Develop and harmonize new research. \\- Strengthen and share research capacity. \\- Facilitate the uptake of evidence in policies and programs. The key activities are: \\- ANH Academy Week: The flagship biannual event featuring learning labs, research conferences, and side events. \\- Working Groups: Accelerate research by sharing methods and approaches. \\- Skills-Based Trainings: Offered via face-to-face gatherings and webinars. \\- Support Center for Agriculture and Nutrition Research (SCANR). \\- Curriculum Resources: For educators in higher education. The 10th annual ANH Academy Week will be held in Tanzania in June 2025, featuring workshops, a research conference, and plenary sessions focused on climate change and health. Given the rise in participation, the Wellcome Trust is invited to consider supporting researchers from low- and middle-income countries.","plannedDates":[{"endDate":"2025-08-31T00:00:00+00:00","startDate":"2025-05-01T00:00:00+00:00"}],"amountAwarded":160000,"Financial Year":"2024/25","Lead Applicant":"Prof Suneetha Venkata Kadiyala","grantProgramme":[{"title":"Discretionary Award"}],"Applicant Surname":"Kadiyala","Approval Committee":"Discretionary Award decision meeting","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":160000},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-328709_Z_25_Z","data":{"id":"360G-Wellcome-328709_Z_25_Z","title":"Africa Oculomics Research Programme: harnessing ocular biomarkers to transform health  ","Region":"London","currency":"GBP","awardDate":"2025-09-02T00:00:00+00:00","Internal ID":"328709/Z/25/Z","description":"Our vision is to unlock the potential of Oculomics to better understand, predict, diagnose and manage systemic and ocular disease, to improve health outcomes and equity for African populations. Oculomics is the emerging field of study into relationships between the eyes and systemic health and disease. It is being transformed by advances in high-resolution ocular imaging coupled with recent advances in artificial intelligence (AI), particularly deep learning. We will conduct ocular phenotyping and imaging studies, repeated five years apart, nested within an existing general population cohort in Uganda. In parallel we will collect clinical, laboratory and image phenotyping data for systemic health states (cardiovascular, neurological, renal, liver, musculoskeletal, mental health), alongside genotyping data. We will use these data to develop, tune and validate AI foundation models to analyse images from this African population for multiple systemic disease and ocular diagnostic tasks. We will investigate cross-sectional and longitudinal relationships between ocular biomarkers and major health conditions, to determine their diagnostic, prognostic and predictive potential. Finally, we will conduct prospective studies to investigate the utility of oculomics supported diagnostics in general health care settings, assessing the suitability and performance of AI-assisted diagnosis, when paired with novel low-cost imaging equipment.","plannedDates":[{"endDate":"2034-02-28T00:00:00+00:00","startDate":"2026-02-01T00:00:00+00:00"}],"amountAwarded":4472832,"Financial Year":"2024/25","Lead Applicant":"Prof Matthew J Burton","grantProgramme":[{"title":"Discovery Award"}],"Applicant Surname":"Burton","Approval Committee":"DSV Interview Committee","Other Applicant(s)":"Prof Moffat J Nyirenda, Prof Annettee Olivia Nakimuli, Prof Pearse Andrew Keane, Dr Simon Arunga","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":4472832},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-329623_Z_25_Z","data":{"id":"360G-Wellcome-329623_Z_25_Z","title":"Tackling the Risks of Aflatoxins and Climate Effects on Child Health in Africa (TRACE)  ","Region":"London","currency":"GBP","awardDate":"2025-08-06T00:00:00+00:00","Internal ID":"329623/Z/25/Z","description":"Our proposal, TRACE, addresses a neglected challenge affecting millions of households in Africa at the intersection of climate change, food safety, and child health. Aflatoxins, toxins produced by fungi in staple crops such as maize and peanuts, pose a growing threat as climate change creates conditions that favour contamination. Exposure has been linked to impaired immunity and malnutrition in children, heightening vulnerability to infections. However, direct evidence remains limited, and aflatoxins are largely absent from climate and child health policy agendas, hindering implementation of mitigation measures. Within the first year of the award, we will connect two decades of climate data to aflatoxin exposure trends, generating the first large-scale empirical evidence of the climate-aflatoxin-child health link. We will then test an intervention package co-designed with communities in Kenya and The Gambia, measuring effects on aflatoxin exposure, acute febrile illness, and vaccine immune responses among children. We will model future health and economic risks under climate change scenarios to inform long-term solutions. Our transdisciplinary team integrates expertise in epidemiology, climate science, immunology, anthropology, food science, and policy engagement. Strong partnerships with communities, governments, and international agencies will ensure findings are rapidly and sustainably embedded into policy and local farming practices.","plannedDates":[{"endDate":"2029-02-28T00:00:00+00:00","startDate":"2026-03-01T00:00:00+00:00"}],"amountAwarded":2731498.3,"Financial Year":"2024/25","Lead Applicant":"Prof Ambrose Agweyu","grantProgramme":[{"title":"Climate Impacts Award"}],"Applicant Surname":"Agweyu","Approval Committee":"Climate Impacts Advisory Committee","Other Applicant(s)":"Prof Jia-Sheng Wang, Dr Neven Stjepan Fuckar, Dr James Jimmy Nyagwange, Prof Salome Bukachi, Dr Modou Jobe, Dr David Githanga","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":"2731498.3"},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-331655_Z_25_Z","data":{"id":"360G-Wellcome-331655_Z_25_Z","title":"Strengthening Adolescent Resilience to Improve Sexual and reproductive hEalth (ARISE) Uganda  ","Region":"London","currency":"GBP","awardDate":"2026-01-13T00:00:00+00:00","Sponsor(s)":"Prof Kara Hanson","Internal ID":"331655/Z/25/Z","description":"This study will generate new evidence on how resilience—defined as positive adaptation despite adversity—shapes sexual and reproductive health (SRH) outcomes among Ugandan adolescents aged 10–19. In Uganda, where adolescents comprise a quarter of the population, rates of HIV, STIs, and unintended pregnancy remain among the highest globally, posing a critical and urgent public health challenge. Drawing on my experience leading research on gender, violence, and adolescent SRH across sub-Saharan Africa, this study applies the Candidacy Framework in a novel way to examine how resilience is shaped, enacted, and constrained across social and structural contexts. Shifting from risk-focused paradigms, it foregrounds adolescents’ strengths—across individual, relational, community, and structural levels—and how these interact with gender and context to influence SRH trajectories. A rigorous mixed-methods design—including longitudinal and cross-sectional surveys, biological testing, participatory approaches, and qualitative methods—will generate generalisable data and deep insight into lived experience. This integrative approach supports nuanced, dynamic analysis of resilience over time. A context-specific tool to measure resilience will be developed and validated, contributing conceptual and empirical innovation. Strong ethical safeguards, youth-led engagement, and collaborative partnerships will ensure cultural relevance and impact. Findings will inform scalable, equity-focused policy and programming aligned to Ugandan and global adolescent health priorities.","plannedDates":[{"endDate":"2034-05-30T00:00:00+00:00","startDate":"2026-06-01T00:00:00+00:00"}],"amountAwarded":3385545,"Financial Year":"2025/26","Lead Applicant":"Dr Nambusi Kyegombe","grantProgramme":[{"title":"Career Development Award"}],"Applicant Surname":"Kyegombe","Approval Committee":"CDA Interview Panel","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"Yes","Total amount including partnership funding":3385545},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-332863_Z_25_Z","data":{"id":"360G-Wellcome-332863_Z_25_Z","title":"NeoShield: Epidemiological Analysis of Neonatal Sepsis and Antimicrobial Resistance Dynamics to Inform Novel Detection Tools in High-Burden Settings  ","Region":"London","currency":"GBP","awardDate":"2025-09-30T00:00:00+00:00","Internal ID":"332863/Z/25/Z","description":"Neonatal healthcare-associated infections (HAIs) are a major cause of mortality and antimicrobial resistance (AMR) in healthcare facilities across sub-Saharan Africa. Of the 2.3 million neonatal deaths annually, an estimated 24% are infection-related, with many linked to outbreaks. Overstretched clinical teams, limited diagnostics, fragmented data, and critical gaps in local pathogen epidemiology and genomics often hinder outbreak detection and response. Integrated, context-appropriate solutions are urgently needed to link local microbiological surveillance to real-time, individual-level care. NeoShield will address these challenges in Malawi and Zambia by generating epidemiological and genomic data on neonatal HAIs and their associated AMR, and by developing and validating an AI-driven Clinical Decision Support Algorithm (CDSA) to support inpatient management of neonatal sepsis. The CDSA will integrate clinical signs, point-of-care diagnostics, and local microbiology trends to support antibiotic treatment decisions aligned with facility, national, and World Health Organisation (WHO) guidelines. Five workstreams will be delivered: (1) Laboratory Strengthening; (2) CDSA Development and Validation; (3) Ward-Level Outbreak Detection with Automated Alerts; (4) Sepsis and Stewardship Intervention Bundle; and (5) Pathogen Whole-Genome Sequencing. NeoShield will produce open-source digital tools, open-access learning resources, peer-reviewed publications, and policy briefs to inform national and global strategies for neonatal infection prevention and AMR surveillance.","plannedDates":[{"endDate":"2028-09-30T00:00:00+00:00","startDate":"2025-10-01T00:00:00+00:00"}],"amountAwarded":1627819.47,"Financial Year":"2024/25","Lead Applicant":"Prof Eric Ohuma","grantProgramme":[{"title":"Discretionary Award"}],"Applicant Surname":"Ohuma","Approval Committee":"Discretionary Award decision meeting","Other Applicant(s)":"Dr Patrick Musicha, Prof Roma Chilengi, Dr James Henry Cross","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":"1627819.47"},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-334348_Z_25_Z","data":{"id":"360G-Wellcome-334348_Z_25_Z","title":"Climate, Children, and Consequences: The Impact of Climate Change on Child Health in Southern Mozambique  ","Region":"London","currency":"GBP","awardDate":"2025-11-05T00:00:00+00:00","Internal ID":"334348/Z/25/Z","description":"As climate change intensifies, extreme heat is becoming a growing threat to health—particularly for young children in low and middle income countries. This project explores how rising temperatures affect child health in Mozambique, a country already facing high burdens of infectious disease, malnutrition, and health system strain. The research will investigate whether heatwaves and high temperatures are linked to increased hospital admissions for illnesses such as diarrhoea, respiratory infections, and fever in children under five. Using 15 years of hospital and climate data from Manhiça District, the project aims to identify patterns and risks, and to generate evidence that can inform health services and climate adaptation planning. The research also supports local collaboration, ensuring Mozambican voices and institutions are central in the design, analysis, and use of findings. The project is part of a broader effort to strengthen climate resilience in child health and contribute to global efforts to reduce climate-related health inequalities. Ultimately, this work will provide much-needed data for policymakers, clinicians, and communities seeking to protect children from the growing health risks of a warming world.","plannedDates":[{"endDate":"2027-12-01T00:00:00+00:00","startDate":"2025-12-01T00:00:00+00:00"}],"amountAwarded":318525,"Financial Year":"2025/26","Lead Applicant":"Dr Sham Lal","grantProgramme":[{"title":"Wellcome Accelerator Awards"}],"Applicant Surname":"Lal","Approval Committee":"Accelerator Awards Advisory Committee","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"Yes","Total amount including partnership funding":318525},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-335478_Z_25_Z","data":{"id":"360G-Wellcome-335478_Z_25_Z","title":"Integrating genomic, clinical and epidemiological data to better understand Mycobacterium tuberculosis transmission and emergence of drug resistance  ","Region":"London","currency":"GBP","awardDate":"2025-11-05T00:00:00+00:00","Internal ID":"335478/Z/25/Z","description":"The rapid emergence and transmission of Mycobacterium tuberculosis (M. tuberculosis) strains resistant to newer drugs, e.g. bedaquiline, threatens global tuberculosis care and prevention. Although drug-resistant tuberculosis accounts for 3% of cases, it consumes over 33% of the budget in South Africa. Research has largely focussed on host and environmental determinants, whilst the role of pathogen genomics in driving transmission and resistance remains under-explored, leaving a gap in knowledge needed to inform effective interventions. This Award will generate foundational insights into how M. tuberculosis lineage and resistance evolution influence transmission. It will accelerate my career by providing pathogen genomics training, enabling me to integrate my academic, clinical and implementation interests in drug-resistant tuberculosis and support the generation of pilot data to underpin a competitive application for a prestigious career development award. The Award will provide protected time to publish manuscripts arising from this work, support my transition to research independence, strengthen collaborations in the Global South and significantly raise my international visibility. By the end of this Award, I will be uniquely positioned to build a high-impact career as an interdisciplinary translational researcher contributing to transmission- cutting public health interventions and enabling precision-guided treatments to improve outcomes for people with drug-resistant tuberculosis.","plannedDates":[{"endDate":"2028-09-30T00:00:00+00:00","startDate":"2026-10-01T00:00:00+00:00"}],"amountAwarded":421926,"Financial Year":"2025/26","Lead Applicant":"Dr Palwasha Yousafzai Khan","grantProgramme":[{"title":"Wellcome Accelerator Awards"}],"Applicant Surname":"Khan","Approval Committee":"Accelerator Awards Advisory Committee","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":421926},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-337458_Z_25_Z","data":{"id":"360G-Wellcome-337458_Z_25_Z","title":"Improving mental health among Ugandan and Ghanaian adolescents through a school-based sleep health intervention: Better Sleep, Better Health  ","Region":"London","currency":"GBP","awardDate":"2026-03-02T00:00:00+00:00","Internal ID":"337458/Z/25/Z","description":"Insomnia can cause depression and anxiety in adolescents. Cognitive behavior therapy for insomnia (CBT-I) is an effective early intervention for depression and anxiety. Focusing on improving sleep can offer a non-stigmatising pathway to improve mental health, but CBT-I is not widely used due to lack of awareness of the importance of sleep for mental health, shortage of trained providers and non-existence of scalable resource-efficient delivery models. We will address the evidence gap of how to deliver CBT-I at scale to adolescents in Africa. In the Foundation Phase, we will build a partnership to design and evaluate scalable CBT-I-based interventions to improve the mental health of secondary school students in Africa. Objectives: 1) To establish a sustainable equitable partnership among researchers, implementation partners, lived- experience experts, WHO and the Ministries of Health and Education in Uganda and Ghana. 2) To adapt a CBT-I-based intervention to ensure scalability and sustainability in Uganda and Ghana, guided by May’s General Theory of Implementation and feasibility case-series. 3) To co-design a cluster- randomised controlled trial to evaluate the implementation, effectiveness, cost-effectiveness and sustainability of these CBT-I-based interventions to reduce depression and anxiety among secondary school students in Uganda and Ghana, using the RE-AIM evaluation framework.","plannedDates":[{"endDate":"2027-07-01T00:00:00+00:00","startDate":"2026-07-01T00:00:00+00:00"}],"amountAwarded":200000,"Financial Year":"2025/26","Lead Applicant":"Prof Helen Anne Weiss","grantProgramme":[{"title":"Directed call - Mental Health – Psychosocial Foundation Phase"}],"Applicant Surname":"Weiss","Approval Committee":"Mental Health Award: Transforming Early Intervention in Young People","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":200000},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-338565_Z_25_Z","data":{"id":"360G-Wellcome-338565_Z_25_Z","title":"INNOVETH: Innovative Health Intervention for Ethiopian Migrant Domestic Workers in the Middle East  ","Region":"London","currency":"GBP","awardDate":"2025-09-30T00:00:00+00:00","Internal ID":"338565/Z/25/Z","description":"Every year, more than 350,000 Ethiopian women migrate to the Middle East legally, and many others illegally, seeking domestic work. Economic crisis, rising unemployment, and internal conflict contribute to this massive migration. The bilateral agreement between the Ethiopian government and each destination country requires recruitment agencies to undertake rigorous pre- migration medical check-up for migrant domestic workers (MDWs). Nevertheless, MDWs in the Middle East are subject to overwork; mental, sexual and reproductive health challenges; and limited healthcare access. Studies on MDWs are mostly exploratory or cross-sectional; longitudinal and intervention studies are lacking. We propose to provide healthcare support to these vulnerable women by leveraging social networks, social media, and innovative technology. In Phase I, we explored key health challenges of MDWs through a scoping review, stakeholder consultation, and analysis of pre-migration data. We hypothesized that, by utilizing epidemiological and data science intelligence methods, we could stratify MDWs based on their level of risk and provide tailored intervention. We developed an intervention package, including training, peer-support and self-help groups, and mobile applications. In Phase II, we propose to i) develop, refine and validate a risk stratification tool, ii) refine and pilot the intervention and iii) implement and evaluate its impact and cost-effectiveness.","plannedDates":[{"endDate":"2029-10-31T00:00:00+00:00","startDate":"2025-11-01T00:00:00+00:00"}],"amountAwarded":425735.14,"Financial Year":"2024/25","Lead Applicant":"Dr Mohammed Sanni Ali","grantProgramme":[{"title":"Discretionary Award"}],"Applicant Surname":"Ali","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":"425735.14"},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-342887_Z_25_Z","data":{"id":"360G-Wellcome-342887_Z_25_Z","title":"Support for IPCC's 7th assessment report meetings  ","Region":"London","currency":"GBP","awardDate":"2025-12-05T00:00:00+00:00","Internal ID":"342887/Z/25/Z","description":"I will be lead author for WGIII chapter 4 and I expect to be attending 1 in person meeting per year.","plannedDates":[{"endDate":"2027-12-31T00:00:00+00:00","startDate":"2026-01-01T00:00:00+00:00"}],"amountAwarded":10504,"Financial Year":"2025/26","Lead Applicant":"Dr Pauline FD Scheelbeek","grantProgramme":[{"title":"Discretionary Award"}],"Applicant Surname":"Scheelbeek","Approval Committee":"Discretionary Award decision meeting","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":10504},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 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Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-343146_Z_25_Z","data":{"id":"360G-Wellcome-343146_Z_25_Z","title":"Open Access Award 2026  ","Region":"London","currency":"GBP","awardDate":"2025-12-15T00:00:00+00:00","Internal ID":"343146/Z/25/Z","description":"No description available","plannedDates":[{"endDate":"2026-12-31T00:00:00+00:00","startDate":"2026-01-01T00:00:00+00:00"}],"amountAwarded":202381,"Financial Year":"2025/26","Lead Applicant":"David Archer","grantProgramme":[{"title":"Open Access Award"}],"Applicant Surname":"Archer","Approval Committee":"Open Access Block Award recommendation meeting","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":202381},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-343250_Z_25_Z","data":{"id":"360G-Wellcome-343250_Z_25_Z","title":"CREATE PhD Programme  ","Region":"London","currency":"GBP","awardDate":"2026-06-12T00:00:00+00:00","Sponsor(s)":"Prof Thushan de Silva","Internal ID":"343250/Z/25/Z","description":"Respiratory viruses can increase bacterial colonisation, density, and secretion from the upper respiratory tract (URT), yet these interactions remain poorly understood—particularly in low- and middle-income countries (LMICs). Characterising these relationships is pivotal in formulating measures to mitigate secondary bacterial infections and bacterial transmission. To address these key knowledge gaps this study investigates the impact of respiratory viruses on the colonisation and transmission dynamics of Streptococcus pneumoniae, Staphylococcus aureus, and Streptococcus pyogenes in Gambian households. Using an existing longitudinal household dataset (TransVir), which includes over 14,000 oral/nasal swabs collected weekly from 349 participants across 52 households, I will: 1.​ Determine the impact of respiratory viruses on URT carriage and density of S. pneumoniae, S. aureus, and S. pyogenes using qPCR-based bacterial quantification. 2.​ Assess how respiratory viral infections influence household transmission of these bacteria using hidden Markov models. 3.​ Characterise virus-induced changes in the URT microbiome through metagenomic sequencing, evaluating shifts in microbial composition and strain-level dynamics. My preliminary analyses indicate that respiratory viruses such as RSV and rhinovirus increase pneumococcal colonisation risk, but SARS-CoV-2 does not. These findings will enhance understanding of viral-bacterial interactions and aims to inform viral and bacterial vaccination strategies and viral pandemic responses in LMICs.","plannedDates":[{"endDate":"2028-01-15T00:00:00+00:00","startDate":"2025-01-15T00:00:00+00:00"}],"amountAwarded":0,"Financial Year":"2025/26","Lead Applicant":"Jack William Goodall","grantProgramme":[{"title":"PhD Studentship for Health Professionals"}],"Applicant Surname":"Goodall","Approval Committee":"Discretionary Award decision meeting","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":0},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-343772_Z_26_Z","data":{"id":"360G-Wellcome-343772_Z_26_Z","title":"Integrated Climate, Food Systems, Nutrition and Health Research in LMICs: barriers, enablers and opportunities  ","Region":"London","currency":"GBP","awardDate":"2026-03-31T00:00:00+00:00","Internal ID":"343772/Z/26/Z","description":"Climate change and environmental degradation are shaping food systems, nutrition and health outcomes, especially in LMICs, while global food systems and diets are contributing to worsening planetary health. Despite growing recognition of these interconnections, research that empirically links these themes remains underdeveloped along many pathways and methodologically fragmented. We will produce an evidence-based needs assessment of the global research ecosystem at the climate–food systems–nutrition–health intersection, with a deliberate focus on LMIC researchers and institutions and their collaborators. We will identify and critically analyse the conceptual, data, capacity and structural barriers that currently limit generation of high- quality interdisciplinary research, alongside opportunities to catalyse research development. Using a mixed qualitative approach, we will (i) map data landscapes, availability and analytic capacities through desk review, and (ii) conduct expert consultation through semi-structured interviews with funders, reviewers and researchers, including applicants to climate–food–health research calls. The project will generate actionable recommendations to inform funders, policymakers and research leaders on how to align investments, strengthen enabling environments and promote interdisciplinary research. Outputs will include a peer-reviewed publication, validation exercise and stakeholder convenings to support a step-change in the generation of policy- relevant evidence linking climate change, food systems, nutrition and health.","plannedDates":[{"endDate":"2027-11-30T00:00:00+00:00","startDate":"2026-04-15T00:00:00+00:00"}],"amountAwarded":232779.6,"Financial Year":"2025/26","Lead Applicant":"Dr Thalia Sparling","grantProgramme":[{"title":"Discretionary Award"}],"Applicant Surname":"Sparling","Approval Committee":"Discretionary Award decision meeting","Other Applicant(s)":"Dr Edward Joy","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":"232779.6"},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-345503_Z_26_Z","data":{"id":"360G-Wellcome-345503_Z_26_Z","title":"Improving the Early Identification and Intervention of Disability-Related Feeding Difficulties amongst Young Children in Uganda  ","Region":"London","currency":"GBP","awardDate":"2026-06-12T00:00:00+00:00","Sponsor(s)":"Dr Femke Bannink Mbazzi","Internal ID":"345503/Z/26/Z","description":"**Research Goal:** To develop and evaluate a contextually relevant Integrated Clinical Care Pathway (ICCP) for early identification and intervention of disability-related feeding difficulties amongst young children (<3 years) with developmental disabilities in Uganda.  **Background:** Feeding difficulties affect up to 80% of children with developmental disabilities, contributing significantly to malnutrition and poor health outcomes, yet remain under-addressed in low-resource settings. Despite disproportionately affecting children in LMICs, there is limited guidance on identification and management approaches within healthcare systems.  **Methods:** This PhD research employs a participatory approach guided by implementation science frameworks. The research will be conducted across two government health centres and one specialist rehabilitation facility in western Uganda, enabling assessment across different healthcare contexts.  **Objectives:** (1) Conduct a scoping review of existing evidence on identification and intervention approaches; (2) Examine facilitators and barriers to accessing high-quality nutritional care through cross-sectional and qualitative assessment; (3) Co-design an ICCP through structured stakeholder workshops; and (4) Evaluate the ICCP's feasibility, acceptability and preliminary impact when implemented in government healthcare facilities.  This research addresses critical evidence gaps whilst developing a model for disability-inclusive healthcare that could be adapted across sub-Saharan Africa, ultimately improving nutritional outcomes for a frequently overlooked vulnerable population.","plannedDates":[{"endDate":"2028-12-31T00:00:00+00:00","startDate":"2026-01-01T00:00:00+00:00"}],"amountAwarded":0,"Financial Year":"2025/26","Lead Applicant":"Miss Fiona Mary Elizabeth Beckerlegge","grantProgramme":[{"title":"PhD Studentship for Health Professionals"}],"Applicant Surname":"Beckerlegge","Approval Committee":"Discretionary Award decision meeting","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":0},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-345549_Z_26_Z","data":{"id":"360G-Wellcome-345549_Z_26_Z","title":"Integrated nutritional care to improve outcomes amongst hospitalised adults with advanced HIV disease (IN-care)  ","Region":"London","currency":"GBP","awardDate":"2026-06-12T00:00:00+00:00","Sponsor(s)":"Prof Joseph Jarvis","Internal ID":"345549/Z/26/Z","description":"Advanced HIV disease (AHD, defined as CD4 20% (3), and 60% of PLWH admitted to hospital are malnourished (5). Energy requirements for PLWH compared to people without HIV are approximately 10% higher when asymptomatic, and 20-50% higher if symptomatic (6), despite this there are currently no guidelines on nutritional support for hospitalised adults with AHD. The aim of my fellowship is to describe nutritional status amongst hospitalised adults with AHD, investigate for associations with mortality, and to co-develop and pilot a feasible and acceptable nutritional intervention to improve outcomes. Objectives: 1\\. To understand and describe the current evidence in nutritional interventions for PLWH by conducting a systematic review. 2\\. To conduct a cohort study of 250 hospitalised adults with AHD to describe the burden of severe malnutrition and to investigate for associations with mortality. 3\\. To co-develop a feasible and acceptable nutritional-supplementation intervention. 4\\. To pilot and evaluate the co-developed intervention amongst 60 hospitalised adults with AHD.","plannedDates":[{"endDate":"2028-08-31T00:00:00+00:00","startDate":"2025-09-01T00:00:00+00:00"}],"amountAwarded":0,"Financial Year":"2025/26","Lead Applicant":"Gila Hale","grantProgramme":[{"title":"PhD Studentship for Health Professionals"}],"Applicant Surname":"Hale","Approval Committee":"Discretionary Award decision meeting","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":0},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-345726_Z_26_Z","data":{"id":"360G-Wellcome-345726_Z_26_Z","title":"Understanding Acquired Epidermodysplasia Verruciformis in Young People Living with HIV in Zimbabwe  ","Region":"London","currency":"GBP","awardDate":"2026-06-12T00:00:00+00:00","Sponsor(s)":"Prof Sinéad Langan","Internal ID":"345726/Z/26/Z","description":"Perinatally-acquired HIV results in early-life immune dysregulation. Historically this led to high mortality rates in childhood. Following the widespread availability of antiretroviral therapy (ART), increasing numbers of people with perinatally-acquired HIV survive into adulthood. Despite effective viral suppression with ART, immune system abnormalities persist, predisposing individuals to a range of comorbidities. One such condition is acquired epidermodysplasia verruciformis (aEV), a disorder characterised by disseminated cutaneous infection with beta human papillomaviruses (HPV). While beta-HPVs are ubiquitous and typically asymptomatic in immunocompetent individuals, some people with HIV can develop extensive and persistent flat warts and pityriasis versicolor-like lesions (aEV). Where the association with HIV is recognised, aEV is highly stigmatising. The associated HPV types, particularly HPV 5 and 8, are potentially oncogenic and there are emerging cases of skin cancer in young people with aEV. There are currently no clear diagnostic criteria and the epidemiology, risk factors, virological drivers, and quality of life impact of aEV in this population remain poorly understood. People with aEV are offered minimal information or support to help them navigate their condition. This study seeks to address these gaps. The findings will inform future research directions, guide clinical management strategies, and support the development of targeted interventions.","plannedDates":[{"endDate":"2028-12-31T00:00:00+00:00","startDate":"2026-01-01T00:00:00+00:00"}],"amountAwarded":0,"Financial Year":"2025/26","Lead Applicant":"Dr Sophie Helen Kelly","grantProgramme":[{"title":"PhD Studentship for Health Professionals"}],"Applicant Surname":"Kelly","Approval Committee":"Discretionary Award decision meeting","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":0},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}},{"grant_id":"360G-Wellcome-351087_Z_26_Z","data":{"id":"360G-Wellcome-351087_Z_26_Z","title":"Rethinking Misinformation, Health and Human Security  ","Region":"London","currency":"GBP","awardDate":"2026-06-25T00:00:00+00:00","Internal ID":"351087/Z/26/Z","description":"Misinformation and disinformation have been ranked by the World Economic Forum and United Nations as top global risks, above extreme weather, armed conflict, and cyber warfare. Their impact on health is severe and growing – from suspended clinical trials and the disruption of vaccination and other health programmes, to climate science denialism and the systematic erosion of trust in health institutions. Yet current response frameworks remain largely reactive and narrowly focused on correcting false information, when the most damaging narratives often operate through emotional manipulation, fear polarisation, undermining of trust, and distortion of perceived social norms - not explicit falsehoods. The Lancet Commission on “Rethinking Misinformation, Health and Human Security” will reframe the dominant understanding of misinformation and operationalise the concept of ‘signal distortion’ as an actionable framework and develop and test ways of intervening to enrich the integrity of the information ecosystem – identifying where and how to intervene to improve the overall quality of information ecosystems while working to build underlying trust. This approach is designed to be operationalised and to outlive the Commission. The Commission will generate clear, policy-targeted recommendations for the audiences best positioned to act – health ministries, multilateral institutions, research institutions, media organisations, technology platforms, and civil society.","plannedDates":[{"endDate":"2029-07-31T00:00:00+00:00","startDate":"2026-08-01T00:00:00+00:00"}],"amountAwarded":305989.2,"Financial Year":"2025/26","Lead Applicant":"Prof Heidi J Larson","grantProgramme":[{"title":"Discretionary Award"}],"Applicant Surname":"Larson","Approval Committee":"Discretionary Award decision meeting","fundingOrganization":[{"id":"GB-CHC-210183","name":"The Wellcome Trust"}],"recipientOrganization":[{"id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine","name":"London School of Hygiene & Tropical Medicine","addressCountry":"United Kingdom","addressLocality":"London"}],"Has the grant transferred?":"No","Research conducted at multiple locations?":"No","Total amount including partnership funding":"305989.2"},"data_license":{"url":"https://creativecommons.org/licenses/by/4.0/","name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"},"publisher":{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"},"recipients":[{"self":"https://api.threesixtygiving.org/api/v1/org/360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine/","org_id":"360G-Wellcome-ORG:London-School-of-Hygiene-&-Tropical-Medicine"}],"funders":[{"self":"https://api.threesixtygiving.org/api/v1/org/GB-CHC-210183/","org_id":"GB-CHC-210183"}],"additional_data_metadata":{"source_license":"https://creativecommons.org/licenses/by/4.0/","sources_metadata":{"codeListLookup":{"license":"https://creativecommons.org/licenses/by/4.0/"},"locationLookup":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrgInfos":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"},"recipientOrganizationLocation":{"license":"https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/"}},"source_license_name":"Creative Commons Attribution 4.0 International (CC BY 4.0)"}}]}